Rapid progression of a low-grade follicular lymphoma with foci of high proliferation index and BCL6 rearrangement into a diffuse large B-cell lymphoma: A case report and review of the literature
Follicular lymphoma (FL) is a common type of non-Hodgkin lymphoma, characterized by the translocation t(14;18) IGH/BCL2 that usually runs an indolent course.It has been known to transform into diffuse large B-cell lymphoma (DLBCL).While the exact mechanism of this transformation is unknown, several contributing genetic changes have been identified.